| Importance of the Pathophysiology of Hypertension |
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It is a silent killer with symptoms that are very common, but can point to a number of other maladies. As such it is hard to diagnose the ailment by any means except a blood pressure check. It is very much possible to identify the disease l at an early stage by getting your blood pressure checked regularly. If diagnosed at an early stage, the disease can be treated by modifying the risk factors and without resorting to medications. There have been quite a few developments in the field of pathophysiology of hypertension.. Pathophysiology of hypertension shows the close correlation between structural and functional aspects of hypertension that help us to understand the disease from various angles. It is seen that in a small number of hypertensive patients (between 2% and 5%), the causes of their high blood pressure is underlying renal and adrenal diseases. However, no apparent single cause can be found and these cases are usually tagged as those of essential hypertension. Normal blood pressure is maintained through a number of physiological means and any disturbance can cause essential hypertension. Mentioned below are some of the physiological factors involved in expansion of essential hypertension such as cardiac output, peripheral resistance, renin-angiotensin-aldosterone system, autonomic nervous system, bradykinin, endothelin, endothelial derived relaxing factor or nitric oxide and ANP (atrial natriuretic peptide). A normal balance in all of these factors can result in normal blood pressure, In United States of America, almost half of the population over the age of 65 has essential hypertension. This group of people is prone to heart attack, stroke and other sorts of diseases. These risks can be considerably lowered through treatment of blood pressure. In order to do so it is important that the complex pathophysiology of hypertension is carefully understood, and hypertension is rationally and systemically treated. |